Absence of nephritogenic GBM antigen(s) in some patients with hereditary nephritis
نویسندگان
چکیده
منابع مشابه
Nephritogenic antibodies in lupus nephritis.
A critical discussion of data on the possible role of IgG3 cryoglobulins, cross-reactive anti-DNA antibodies and anti-DNA idiotypes in the pathogenesis of lupus nephritis is included. A further possibility involving cationic nuclear autoantigens is presented in detail. Histone was employed as a model antigen, representative of this group. Histones were shown to have high affinity for the rat GB...
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چکیده ندارد.
15 صفحه اولPathology of hereditary nephritis.
This report describes the renal pathology in three siblings with hereditary nephritis. All three cases showed combined features of chronic glomerulonephritis, pyelonephritis, and interstitial nephritis. Foam cells were seen in only one case. These findings support the contention of Krickstein, Gloor, and Balogh (1966) that the renal changes in hereditary nephritis are those of a mixed nephritis.
متن کاملSuppression by cyclosporin A of anti-GBM nephritis in rats.
The suppressive effect of cyclosporin A (CyA) on the development of glomerulonephritis was evaluated in rats with either original- or crescentic-type anti-glomerular basement membrane (GBM) nephritis. CyA (2.5, 10 or 20 mg/kg) was given p.o. daily to original-type anti-GBM nephritic rats for 10 days from the day after the injection of anti-GBM serum. The development of the nephritis was dose-de...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1982
ISSN: 0085-2538
DOI: 10.1038/ki.1982.72